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Management of Acute Repetitive Seizures: Defining the Role of Rectal Diazepam Gel

Lowe, Matthew N.; Palmer, Katharine J.; Wilde, Michelle I. - In: Disease Management and Health Outcomes 8 (2000) 6, pp. 355-368

Acute repetitive seizures, more commonly known as cluster, crescendo or sequential seizures, are defined as episodes of increased seizure activity occurring in patients with refractory epilepsy who are already receiving stable regimens of anticonvulsants. They lie in the seizure spectrum between...

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Recombinant Human Erythropoietin as an Alternative to Blood Transfusion in Cancer-Related Anaemia

Engert, Andreas - In: Disease Management and Health Outcomes 8 (2000) 5, pp. 259-272

As physicians become more aware of the need to treat anaemia in their patients with cancer, they have to consider 2 treatment options: red blood cell transfusion or recombinant human erythropoietin [epoetin alfa; epoetin beta]. Healthcare systems are under increasing pressure to lower costs while...

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Inhaled Fluticasone Propionate: A Pharmacoeconomic Review of its Use in the Management of Asthma

Lamb, Harriet M.; Culy, Christine R.; Faulds, Diana - In: PharmacoEconomics 18 (2000) 5, pp. 487-510

Contemporary asthma management guidelines list inhaled corticosteroids as the preferred controller medication for patients with persistent asthma. Despite the availability of explicit guidelines, there is evidence that these agents are underused and that guidelines are not always adhered to....

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Impact of Allergic Rhinitis Treatment on Quality of Life

Tripathi, Anju; Patterson, Roy - In: PharmacoEconomics 19 (2001) 9, pp. 891-899

population, is a significant health and economic burden, and severely impairs quality of life. Two main instruments, Medical … Outcomes Study 36-Item Short Form health survey (SF-36) and Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) have been …

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The Concept of Clinically Meaningful Difference in Health-Related Quality of Life Research: How Meaningful is it?

Hays, Ron D.; Woolley, J. Michael - In: PharmacoEconomics 18 (2000) 5, pp. 419-423

It is generally believed that small differences in health-related quality of life (HR-QOL) may be statistically …

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Quality-of-Life Assessment in Osteoporosis: Health-Status and Preference-Based Measures

Tosteson, Anna N.A.; Hammond, Cristina S. - In: PharmacoEconomics 20 (2002) 5, pp. 289-303

Health-status and preference-based approaches to assessing health-related quality of life (HR-QOL) in osteoporosis are … reviewed. Osteoporosis-targeted health-status instruments [i.e. Osteoporosis Quality-of-Life Questionnaire (OQLQ), Osteoporosis … diverse clinical and epidemiological studies, are described first. Preference-based approaches to osteoporosis health …

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Valuing Health-Related Quality of Life: A Review of Health State Valuation Techniques

Green, Colin; Brazier, John; Deverill, Mark - In: PharmacoEconomics 17 (2000) 2, pp. 151-165

Given the growing need to value health-related quality of life, a review of the literature relating to health state …, TTO and PTO) are best placed to reflect the strength of preference for health, with the choice between these techniques …

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Pharmacoeconomic Considerations in Treating Ovarian Cancer

Bodurka-Bevers, Diane; Sun, Charlotte C.; Gershenson, … - In: PharmacoEconomics 17 (2000) 2, pp. 133-150

Ovarian cancer is the leading cause of death in women with gynaecological cancers. The most common type of ovarian cancer is epithelial ovarian cancer. Referred to as the `silent' killer, this disease is difficult to detect because of the lack of specific symptoms. The majority of women who have...

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Dodel, Richard C.; Berger, Karin; Oertel, Wolfgang H. - In: PharmacoEconomics 19 (2001) 10, pp. 1013-1038

of motor complications on indirect costs. Several studies have shown that health-related quality of life (HR-QOL) is …

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Mirtazapine: A Pharmacoeconomic Review of its Use in Depression

Holm, Kristin J.; Jarvis, Blair; Foster, Rachel H. - In: PharmacoEconomics 17 (2000) 5, pp. 515-534

Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). The antidepressant efficacy of mirtazapine has been established in randomised, double-blind comparative studies. Mirtazapine has generally shown similar efficacy to other antidepressants. There is evidence for a...

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